Contents at a Glance
Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Part 1: Getting Started with Biostatistics . . . . . . . . . . . . . . . . . . . . . . 5
CHAPTER 1: Biostatistics 101. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
CHAPTER 2: Overcoming Mathophobia: Reading and Understanding
Mathematical Expressions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
CHAPTER 3: Getting Statistical: A Short Review of Basic Statistics. . . . . . . . . . . . . . . . . 29
Part 2: Examining Tools and Processes. . . . . . . . . . . . . . . . . . . . . . . . 51
CHAPTER 4: Counting on Statistical Software . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
CHAPTER 5: Conducting Clinical Research. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
CHAPTER 6: Taking All Kinds of Samples. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77
CHAPTER 7: Having Designs on Study Design. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87
Part 3: Getting Down and Dirty with Data . . . . . . . . . . . . . . . . . . . . 99
CHAPTER 8: Getting Your Data into the Computer. . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
CHAPTER 9: Summarizing and Graphing Your Data. . . . . . . . . . . . . . . . . . . . . . . . . . . 111
CHAPTER 10: Having Confidence in Your Results. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129
Part 4: Comparing Groups. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139
CHAPTER 11: Comparing Average Values between Groups. . . . . . . . . . . . . . . . . . . . . 141
CHAPTER 12: Comparing Proportions and Analyzing Cross-Tabulations. . . . . . . . . . 159
CHAPTER 13: Taking a Closer Look at Fourfold Tables. . . . . . . . . . . . . . . . . . . . . . . . . . 173
CHAPTER 14: Analyzing Incidence and Prevalence Rates in Epidemiologic Data. . . . 191
Part 5: Looking for Relationships with Correlation
and Regression. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
CHAPTER 15: Introducing Correlation and Regression. . . . . . . . . . . . . . . . . . . . . . . . . . 201
CHAPTER 16: Getting Straight Talk on Straight-Line Regression. . . . . . . . . . . . . . . . . . 213
CHAPTER 17: More of a Good Thing: Multiple Regression. . . . . . . . . . . . . . . . . . . . . . . 233
CHAPTER 18: A Yes-or-No Proposition: Logistic Regression. . . . . . . . . . . . . . . . . . . . . 249
CHAPTER 19: Other Useful Kinds of Regression. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 271
CHAPTER 20: Getting the Hint from Epidemiologic Inference. . . . . . . . . . . . . . . . . . . . 291